DOI: https://doi.org/10.22141/2224-1507.7.3.2017.116864

Vitamin D3 deficiency and its role in the development of metabolic disorders

Yu.I. Komisarenko, M.M. Veliky, L.I. Apukhovska

Abstract


Data are presented on the effect of vitamin D3 on calcium-phosphorus and carbohydrate metabolism, as well as on the functional activity of pancreatic β cells against the background of hypovitaminosis D and in experimental diabetes in mice. Some mechanisms of disturbance of vitamin D3 metabolism and the results of its clinical use in patients with type 1 and type 2 diabetes mellitus are described.


Keywords


hypovitaminosis D; carbohydrate metabolism; experimental diabetes; D deficiency in type 1 and type 2 diabetes mellitus



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