Features of the influence of keltican and polarizing light on signs of neuropathic pain in combination therapy of diabetic polyneuropathy
Background. Diagnosis and treatment of diabetic polyneuropathy is of particular importance for patients with diabetes mellitus and can lead to severe consequences. The purpose of the study was to increase the effectiveness of treatment for neuropathic pain by inclusion of keltican and polarizing light into the comprehensive therapy of diabetic polyneuropathy. Materials and methods. We examined 99 patients with type 2 diabetes mellitus complicated by diabetic polyneuropathy. Patients were divided into 3 groups: the control group included 32 patients who received standard treatment, 32 persons in the second group additionally received 1 capsule of keltican three times a day for a month, and 35 diabetic patients of the third group were assigned additional 12 procedures of polarizing light. The assessment of neuropathic pain severity was performed using a DN4 modified questionnaire. Results. The positive clinical effect of treatment was observed in all groups after 12 days of treatment, and maintained for 3 months in groups 2 and 3, and it lasted for 6 months in the group with additional prescription of keltican. Conclusions. The inclusion of keltican and polarizing light in the standard comprehensive therapy of diabetic polyneuropathy increases the clinical efficacy of neuropathic pain treatment. Using a DN4 questionnaire with a modified evaluation scale to assess neuropathic pain severity helps to optimize diagnosis of such complications in diabetic patients.
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