DOI: https://doi.org/10.22141/2224-1507.9.3.2019.178640

Nutrition as both risk factor and intervention in rheumatic diseases

О.G. Puzanova

Abstract


The purpose of the paper is to provide a review of the effects of nutrition as a risk factor and intervention in the aspect of rheumatic diseases. Using information analysis methods, more than 100 special literature sources have been studied, including evidence based medicine computer databases. The significance of nutrition as a risk factor for the development and outcomes, first of all for rheumatoid arthritis and gout, is proved in large observational studies, systematic reviews and meta-analysis dedicated to both preventive and therapeutic potential as well as to safety of different food products, diets, micronutrients and probiotics, including in connection with associated main risk factors of non-infectious diseases (tobacco smoking, alcohol consumption, increased body mass index). The pathogenetic role of nutrition is considered in the context of its influence on gut microbiota. Necessity of the randomized controlled trials is shown in order to assess the protective potential of different nutritional patterns, as well as the effects of modified Mediterranean diet, some dietary supplements and probiotics intake in rheumatic diseases, and as a result — to develop special guidelines on nutrition in rheumatic patients. There is a sufficient evidence base of preventive counse­ling of such patients on nutritional issues with the aim of cardiovascular risk reduction.

Keywords


rheumatic diseases; nutrition; risk factor; intervention; review

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References


Dinu M, Abbate R, Gensini GF, Casini A, Sofi F. Vegetarian, vegan diets and multiple health outcomes: A systematic review with meta­analysis of observational studies. Crit Rev Food Sci Nutr. 2017 Nov 22;57(17):3640­3649. doi: 10.1080/10408398.2016.1138447.

Stange R, Leitzmann C, editors. Ernährung und Fasten als Therapie. Deutschland: Springer­Verlag GmbH; 2017. 348 p. doi: 10.1007/978­3­662­54475­4.

Forsyth C, Kouvari M, D’Cunha NM, et al. The effects of the Mediterranean diet on rheumatoid arthri-tis prevention and treatment: a systematic review of human prospective studies. Rheumatol Int. 2018 May;38(5):737­747. doi: 10.1007/s00296­017­3912­1.

Grygielska Y, Raciborski F, Kłak A, Owoc J. The impact of nutrition and generally available products such as nicotine and alcohol on rheumatoid arthritis − review of the literature. Reumatologia. 2018;56(2):121­127. doi: 10.5114/reum.2018.75524.

Keyβer G. Ernährung bei rheumatischen Erkrankungen. Arthritis und Rheuma. 2018;38(04):258­264. doi: 10.1055/s­0038­1669793.

Petersson S, Philippou E, Rodomar C, Nikiphorou E. The Mediterranean diet, fish oil supplements and rheumatoid arthritis outcomes: evidence from clinical trials. Autoimmun Rev. 2018 Nov;17(11):1105­1114. doi: 10.1016/j.autrev.2018.06.007.

Philippou E, Nikiphorou E. Are we really what we eat? Nutrition and its role in the onset of rheumatoid arthritis. Autoimmun Rev. 2018 Nov;17(11):1074­1077. doi: 10.1016/j.autrev.2018.05.009.

Niklas K, Niklas AA, Majewski D, Puczczewicz M. Rheumatic diseases induced by drugs and environ-mental factors: the state­of­the­art − part one. Reumatologia. 2016;54(4):165­169. doi: 10.5114/reum.2016.62470.

Maeda Y, Kumanogoh A, Takeda K. Altered composition of gut microbiota in rheumatoid arthritis pa-tients. Nihon Rinsho Meneki Gakkai Kaishi. 2016;39(1):59­63. doi: 10.2177/jsci.39.59.

Kang Y, Cai Y, Zhang X, Kong X, Su J. Altered gut microbiota in rheumatoid arthritis: implications for treatment. Z Rheumatol. 2017 Jun;76(5):451­457. doi: 10.1007/s00393­016­0237­5.

Schorpion A, Kolasinski SL. Can Probiotic Supplements Improve Outcomes in Rheumatoid Arthritis? Curr Rheumatol Rep. 2017 Nov 2;19(11):73. doi: 10.1007/s11926­017­0696­y.

Yang L, Wang L, Wang X, Xian CL, Lu H. A Possible Role of Intestinal Microbiota in the Pathogenesis of Ankylosing Spondylitis. Int J Mol Sci. 2016 Dec 17;17(12). pii: E2126. doi: 10.3390/ijms17122126.

Silvermann GJ. The microbiome in SLE pathogenesis. Nat Rev Rheumatol. 2019 Feb;15(2):72­74. doi: 10.1038/s41584­018­0152­z.

Jin Z, Xiang C, Cai Q, Wei X, He J. Alcohol consumption as a preventive factor for developing rheuma-toid arthritis: a dose­response meta­analysis of prospective studies. Ann Rheum Dis. 2014 Nov;73(11):1962­7. doi: 10.1136/annrheumdis­2013­203323.

Arleevskaya M, Kravtsova O, Lemerle L, Renaudineau Y, Tsibulkin AP. How rheumatiod arthritis can result from provocation of the immune system by microorganisms and viruses. Front Microbiol. 2016 Aug 17;7:1296. doi: 10.3389/fmicb.2016.01296.

Masuko K. A Potential Benefit of “Balanced Diet” for Rheumatoid Arthritis. Front Med (Lausanne). 2018 May 15;5:141. doi: 10.3389/fmed.2018.00141.

Skoczyńska M, Świerkot J. The role of diet in rheumatoid arthritis. Reumatologia. 2018;56(4):259­267. doi: 10.5114/reum.2018.77979.

Andreica I, Braun J. Spondyloarthritiden und Lebensstil (Lifestyle). Arthritis und Rheuma. 2018;38(04):246­252. doi: 10.1055/s­0038­1669791.

Kiltz U, Braun J, Tausche AK. Gicht und Lifestyle. Arthritis und Rheuma. 2018;38(04):253­257. doi: 10.1055/s­0038­1669792.

Hu Y, Sparks JA, Malspeis S, et al. Long­term dietary quality and risk of developing rheumatoid arthritis in women. Ann Rheum Dis. 2017 Aug;76(8):1357­1364. doi: 10.1136/annrheumdis­2016­210431.

Tuaeva NO, Nosyrev AE, Renaudineau Y, Arleevskaya MI. Psychological stress and rheumatoid arthritis – interference of pathogenetic mechanisms. Rheumatology Science and Practice. 2019;57(1):83­90. doi:10.14412/1995­4484­2019­83­90. (in Russian).

Mursu J, Robien K, Harnach LJ, Park K, Jacobs DR Jr. Dietary supplements in older women: the Iowa Women’s Health Study. Arch Intern Med. 2011 Oct 10;171(18):1625­33. doi: 10.1001/archinternmed.2011.445.

Crowson CS, Matteson EL, Myasoedova E, et al. The lifetime risk of adult­onset rheumatoid arthritis and other inflammatory autoimmune rheumatic diseases. Arthritis Rheum. 2011 Mar;63(3):633­9. doi: 10.1002/art.30155.

Hodge AM, Bassett JK, Dugue PA, et al. Dietary inflammatory index or Mediterranean score as risk fac-tors for total and cardiovascular mortality. Nutr Metab Cardiovasc Dis. 2018 May;28(5):461­469. doi: 10.1016/j.numecd.2018.01.010.

Kitas GD, Gabriel SE. Cardiovascular disease in rheumatoid arthritis: state of the art and future per-spectives. Ann Rheum Dis. 2011 Jan;70(1):8­14. doi: 10.1136/ard.2010.142133.

Zou K, Xiao FK, Li HY, et al. Risk of cardiovascular disease in Chinese patients with rheumatoid arthri-tis: A cross­sectional study based on hospital medical records in 10 years. PLoS One. 2017 Jul 5;12(7):e0180376. doi: 10.1371/journal.pone.0180376.

Lu B, Solomon DH, Costenbader KH, Karlson EW. Alcohol consumption and risk of incident of rheu-matoid arthritis in women: a prospective study. Arthritis Rheumatol. 2014 Aug;66(8):1998­2005. doi: 10.1002/art.38634.

Colditz GA, Philipott SE, Hunkinson SE. The Impact of the Nurses’ Health Study on Population Health: Prevention, Translation, and Control. Am J Public Health. 2016 Sep;106(9):1540­5. doi: 10.2105/AJPH.2016.303343.

Barbhaiya M, Lu B, Sparks JA, et al. Influence of Alcohol Consumption on the Risk of Systemic Lupus Erythematosus Among Women in the Nurses’ Health Study Cohort. Arthritis Care Res (Hoboken). 2017 Mar;69(3):384­392. doi: 10.1002/acr.22945.

Liu X, Tedeschi SK, Barbhaiya M, et al. Impact and timing of smoking cessation on reducing risk for rheumatoid arthritis among women in the Nurses’ Health Studies. Arthritis Care Res (Hoboken). 2019 Jul;71(7):914­924. doi: 10.1002/acr.23837.

Karlson EW, Mandl LA, Hankinson SE, Grodstein F. Do breast­feeding and other reproductive factors influence future risk of rheumatoid arthritis: Results from the Nurses’ Health Study. Arthritis Rheum. 2004 Nov;50(11):3458­67. doi: 10.1002/art.20621.

Karlson EW, Mandl LA, Aweh GN, Grodstein F. Coffee consumption and risk of rheumatoid arthritis. Arthritis Rheum. 2003 Nov;48(11):3055­60. doi: 10.1002/art.11306.

Parks CG, D’Aloisio AA, DeRoo LA, et al. Childhood socioeconomic factors and perinatal characteris-tics influence development of rheumatoid arthritis in adulthood. Ann Rheum Dis. 2013 Mar;72(3):350­6. doi: 10.1136/annrheumdis­2011­201083.

Kallberg H, Jacobsen S, Bengtsson C, et al. Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case­control studies. Ann Rheum Dis. 2009 Feb;68(2):222­7. doi: 10.1136/ard.2007.086314.

Kallberg H, Ding B, Padyukov L, et al. Smoking is a major preventable risk factor for rheumatoid arthri-tis: estimation of risks after various exposures to cigarette smoke. Ann Rheum Dis. 2011 Mar;70(3):508­11. doi: 10.1136/ard.2009.120899.

Di Giusepe D, Discaciati A, Orsini N, Wolk A. Cigarette smoking and risk of rheumatoid arthritis: a dose­response meta­analysis. Arthritis Res Ther. 2014 Mar 5;16(2):R61. doi: 10.1186/ar4498.

Heliõvaara M, Aho K, Knekt P, Impivaara O, Reunanen A, Aromaa A. Coffee consumption, rheumatoid factor, and the risk of rheumatoid arthritis. Ann Rheum Dis. 2000 Aug;59(8):631­5. doi: 10.1136/ard.59.8.631.

Mikuls TR, Cerhan JR, Criswell LA, et al. Coffee, tea, and caffeine consumption and risk of rheumatoid arthritis: results from the Iowa Women’s Health Study. Arthritis Rheum. 2002 Jan;46(1):83­91. doi: 10.1002/1529­0131(200201)46:13.0.CO;2­D.

Scott IC, Tan R, Stahl D, Steer S, Lewis CM, Cope AP. The protective effect of alcohol on developing rheumatoid arthritis: a systematic review and meta­analysis. Rheumatology (Oxford). 2013 May;52(5):856­67. doi: 10.1093/rheumatology/kes376.

Nissen MJ, Gabay C, Scherer A, et al. The effect of alcohol on radiographic progression in rheumatoid arthritis. Arthritis Rheum. 2010 May;62(5):1265­72. doi: 10.1002/art.27388. doi: 10.1002/art.27388.

DeChristopher LR, Uribarri J, Tucker KL. Intake of high­fructose corn syrup sweetened soft drinks, fruit drinks and apple juice is associated with prevalent arthritis in US adults, aged 20­30 years. Nutr Di-abetes. 2016 Mar 7;6:e199. doi: 10.1038/nutd.2016.7.

Westhoff G, Rau R, Zink A. Radiographic joint damage in early rheumatoid arthritis is highly dependent on body mass index. Arthritis Rheum. 2007 Nov;56(11):3575­82. doi: 10.1002/art.23033.

Ajeganova S, Andersson MI, Hafstrom I, BARFOT Study Group. Association of obesity with worse dis-ease activity in rheumatoid arthritis as well as with comorbidities: a long­term follow­up from disease onset. Arthritis Care Res (Hoboken). 2013 Jan;65(1):78­87. doi: 10.1002/acr.21710.

Sundstrom B, Johansson I, Kantapaa­Dahlqvist S. Interaction between dietary sodium and smoking in-crease the risk for rheumatoid arthritis: results from a nested case­control study. Rheumatology (Ox-ford). 2015 Mar;54(3):487­93. doi: 10.1093/rheumatology/keu330.

de Hair MJ, Landewe RB, van de Sande MG, et al. Smoking and overweight determine the likelihood of developing rheumatoid arthritis. Ann Rheum Dis. 2013 Oct;72(10):1654­8. doi: 10.1136/annrheumdis­2012­202254.

Pattison DJ, Symmons DP, Young A. Does diet have a role in the etiology of rheumatoid arthritis? Proc Nutr Soc. 2004 Feb;63(1):137­43.

Benito­Garcia E, Feskanich D, Hu FB, Mandl LA, Karlson EW. Protein, iron, and meat consumption and risk for rheumatoid arthritis: a prospective cohort study. Arthritis Res Ther. 2007;9(1):R16. doi: 10.1186/ar2123.

Pedersen M, Stripp C, Klarlung M, Olsen SF, Tønneland AM, Frisch M. Diet and risk of rheumatoid arthritis in a prospective cohort. J Rheumatol. 2005 Jul;32(7):1249­52.

Sköldstam L, Larsson L, Lindsröm FD. Effect of fasting and lactovegetarian diet on rheumatoid arthritis. Scand J Rheumatol. 1979;8(4):249­55.

Kjeldsen­Kragh J, Haugen M, Borchgrevnik CF, et al. Controlled trial of fasting and one­year vegetarian diet in rheumatoid arthritis. Lancet. 1991 Oct 12;338(8772):899­902. doi: 10.1016/0140­6736(91)91770­u.

Klareskog L, Catrina AI, Paget S. Rheumatoid arthritis. Lancet. 2009 Feb 21;373(9664):659­72. doi: 10.1016/S0140­6736(09)60008­8.

He J, Wang Y, Feng M, et al. Dietary intake and risk of rheumatoid arthritis − a cross section multicenter study. Clin Rheumatol. 2016 Dec;35(12):2901­2908. doi: 10.1007/s10067­016­3383­x.

Shai I, Schwarzfuchs D, Henkin Y, et al. Weight loss with a low­carbohydrate, Mediterranean, or low­fat diet. N Engl J Med. 2008;359:229­241. doi: 10.1056/NEJMoa0708681.

Hu Y, Costenbader KH, Gao X, Hu FB, Karlson EW, Lu B. Mediterranean diet and incidence of rheu-matoid arthritis in women. Arthritis Care Res (Hoboken). 2015 May;67(5):597­606. doi: 10.1002/acr.22481.

Cerhan JR, Saag KG, Merlino LA, Mikuls TR, Criswell LA. Antioxidant micronutrients and risk of rheumatoid arthritis in cohort of older women. Am J Epidemiol. 2003 Feb 15;157(4):345­54.

Pattison DJ, Symmons DP, Lunt M, et al. Dietary beta­cryptoxantin and inflammatory polyarthritis: re-sults from a population­based prospective study. Am J Clin Nutr. 2005 Aug;82(2):451­5. doi: 10.1093/ajcn.82.2.451.

Merlino LA, Curtis J, Mikuls TR, et al. Vitamin D intake is inversely associated with rheumatoid arthri-tis: results from the Iowa Women’s Health Study. Arthritis Rheum. 2004 Jan;50(1):72­7. doi: 10.1002/art.11434.

Racovan M, Walitt B, Collins CE, et al. Calcium and vitamin D supplementation and incident rheuma-toid arthritis: the Women’s Health Initiative Calcium plus Vitamin D trial. Rheumatol Int. 2012 Dec;32(12):3823­30. doi: 10.1007/s00296­011­2268­1.

Hagen KB, Byfuglien MG, Falzon L, Olsen SU, Smedslung G. Dietary interventions for rheumatoid ar-thritis. Cochrane Database Syst Rev. 2009 Jan 21;(1):CD006400. doi: 10.1002/14651858.CD006400.pub2.

Kavanaghi R, Workman E, Nash O, Smith M, Hazleman BL, Hunter JO. The effects of elemental diet and subsequent food reintroduction on rheumatoid arthritis. Br J Rheumatol. 1995 Mar;34(3):270­3.

Holst­Jensen SE, Pfeiffer­Jensen M, Monsrud M, et al. Treatment of rheumatoid arthritis with a peptide diet: a randomized, controlled trial. Scand J Rheumatol. 1998;27(5):329­36.

Hafstrom I, Ringertz B, Spångberg A, et al. A vegan diet free of gluten improves the signs and symptoms of rheumatoid arthritis: the effects on arthritis correlate with a reduction in antibodies to food antigens. Rheumatology (Oxford). 2001 Oct;40(10):1175­9. doi: 10.1093/rheumatology/40.10.1175.

Khanna S, Jaiswai KS, Gupta B. Managing Rheumatoid Arthritis with Dietary Interventions. Front Nutr. 2017 Nov 8;4:52. doi: 10.3389/fnut.2017.00052.

Podas T, Nightingale JM, Oldham R, Roy S, Sheehan NJ, Mayberry JF. Is rheumatoid arthritis a disease that starts in the intestine? A pilot study comparing an elemental diet with oral prednisolone. Postgrad Med J. 2007 Feb;83(976):128­31. doi: 10.1136/pgmj.2006.050245.

Haugen M, Kjeldsen­Kragh J, Nordvåg BY, Førre O. Diet and disease symptoms in rheumatic diseases − results of a questionnaire based survey. Clin Rheumatol. 1991 Dec;10(4):401­7.

van de Laar MA, van der Korst JK. Food intolerance in rheumatoid arthritis. I. A double blind, con-trolled trial of the clinical effects of elimination of milk allergens and azo dyes. Ann Rheum Dis. 1992 Mar;51(3):298­302. doi: 10.1136/ard.51.3.298.

Müller H, de Toledo FW, Resch KL. Fasting followed by vegetarian diet in patients with rheumatoid ar-thritis: a systematic review. Scand J Rheumatol. 2001;30(1):1­10.

Sköldstam L, Hagfors I, Johansson G. An experimental study of a Mediterranean diet intervention for patients with rheumatoid arthritis. Ann Rheum Dis. 2003 Mar;62(3):208­14. doi: 10.1136/ard.62.3.208.

Tedeschi SK, Bathon JM, Giles JT, Lin TC, Yoshida K, Solomon DH. Relationship Between Fish Con-sumption and Disease Activity in Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2018 Mar;70(3):327­332. doi: 10.1002/acr.23295.

Matsumoto Y, Sugioka Y, Tada M, et al. Monounsaturated fatty acids might be key factors in the Medi-terranean diet that suppress rheumatoid arthritis disease activity: The TOMORROW study. Clin Nutr. 2018 Apr;37(2):675­680. doi: 10.1016/j.clnu.2017.02.011.

Wu GD, Chen J, Hoffmann C, et al. Linking long­term dietary patterns with gut microbial enterotypes. Science. 2011 Oct 7;334(6052):105­8. doi: 10.1126/science.1208344.

Wong GM. Gut microbiota and cardiometabolic outcomes:influence of dietary patterns and their associ-ated components. Am J Clin Nutr. 2014 Jul;100 Suppl 1:369S­77S. doi: 10.3945/ajcn.113.071639.

Choi EY, Jin JY, Choi JI, Choi IS, Kim SJ. DHA suppresses Prevotella imtermedia lipopolysaccha-ride­induced production of proinflammatory mediators in murine macrophages. Br J Nutr. 2014 Apr 14;111(7):1221­30. doi: 10.1017/S0007114513003681.

Goldberg RG, Katz J. A meta­analysis of the analgesic effects of omega­3 polyunsaturated fatty acid sup-plementation for inflammatory joint pain. Pain. 2007 May;129(1­2):210­23. doi: 10.1016/j.pain.2007.01.020.

Lee YH, Bae SC, Song GG. Omega­3 polyunsaturated fatty acids and the treatment of rheumatoid arthri-tis: a meta­analysis. Arch Med Res. 2012 Jul;43(5):356­62. doi: 10.1016/j.arcmed.2012.06.011.

Gioxari A, Kaliora AC, Marantidou F, Panagiotakos DP. Intake of ω­3 polyunsaturated fatty acids in pa-tients with rheumatoid arthritis: A systematic review and meta­analysis. Nutrition. 2018 Jan;45:114­124.e4. doi: 10.1016/j.nut.2017.06.023.

Kolahi S, Ghorbanihaghijo A, Alizadeh S, et al. Fish oil supplementation decreases serum soluble recep-tor activator of nuclear factor­kappa B ligand/osteoprotegerin ratio in female patients with rheumatoid arthritis. Clin Biochem. 2010 Apr;43(6):576­80. doi: 10.1016/j.clinbiochem.2009.12.011.

Simopoulos AP. The importance of the omega­6/omega­3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med (Maywood). 2008 Jun;233(6):674­88. doi: 10.3181/0711­MR­311.

Fu Y, Li G, Zhang X, et al. Lipid Extract from Hard­Shelled Mussel (Mytilus coruscus) Improves Clini-cal Conditions of Patients with Rheumatoid Arthritis: A Randomized Controlled Trial. Nutrients. 2015 Jan 16;7(1):625­45. doi: 10.3390/nu7010625.

Proudman SM, James MJ, Spargo LD, et al. Fish oil in recent onset rheumatoid arthritis: a randomized, double­blind controlled trial within algorithm­based drug use. Ann Rheum Dis. 2015 Jan;74(1):89­95. doi: 10.1136/annrheumdis­2013­204145.

Remans PH, Sont JK, Wagenaar LW, et al. Nutrient supplementation with polyunsaturated fatty acids and micronutrients in rheumatoid arthritis: clinical and biochemical effects. Eur J Clin Nutr. 2004 Jun;58(6):839­45. doi: 10.1038/sj.ejcn.1601883.

Bae SC, Jung WJ, Lee EJ, Yu R, Sung MK. Effects of antioxidant supplements intervention on the level of plasma inflammatory molecules and disease activity of rheumatoid arthritis patients. J Am Coll Nutr. 2009 Feb;28(1):56­62.

Miller ER 3rd, Pastor­Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta­analysis: high­dosage vitamin E supplementation may increase all­cause mortality. Ann Intern Med. 2005 Jan 4;142(1):37­46. doi: 10.7326/0003­4819­142­1­200501040­00110.

Franco AS, Freitas TQ, Bernardo WM, Pereira RMR. Vitamin D supplementation and disease activity in patients with immune­mediated rheumatic diseases: A systematic review and meta­analysis. Medicine (Baltimore). 2017 Jun;96(23):e7024. doi: 10.1097/MD.0000000000007024.

Wang M, Jiang X, Wu W, Zhang D. A meta­analysis of alcohol consumption and the risk of gout. Clin Rheumatol. 2013 Nov;32(11):1641­8. doi: 10.1007/s10067­013­2319­y.

Choi HK, Willett W, Curhan G. Coffee consumption and risk of incident gout in men: a prospective study. Arthritis Rheum. 2007 Jun;56(6):2049­55. doi: 10.1002/art.22712.

Puzanova O.H. For the anniversary of the German Rheumatological Society: current topics of the united Congress DGRh, DGORh and GKJR. Ukraïns'kij medičnij vìsnik. 2018;1(126):43­48. (in Ukrainian).

Moi JH, Sriranganathan MK, Edwards CJ, Buchbinder R. Lifestyle interventions for chronic gout. Cochrane Database Syst Rev. 2013 May 31;(5):CD010039. doi: 10.1002/14651858.CD010039.pub2.

Andrés M, Sivera F, Falzon L, Buchbinder R, Carmona L. Dietary supplements for chronic gout. Cochrane Database Syst Rev. 2014 Oct 7;(10):CD010156. doi: 10.1002/14651858.CD010156.pub2.

Nielsen SM, Bartels EM, Henriksen M, et al. Weight loss for overweight and obese individuals with gout: a systematic review of longitudinal studies. Ann Rheum Dis. 2017 Nov;76(11):1870­1882. doi: 10.1136/annrheumdis­2017­211472.

Pianta A, Arvikar S, Strle K, et al. Evidence of the Immune Relevance of Prevotella copti, a Gut Mi-crobe, in Patients with Rheumatoid Arthritis. Arthritis Rheumatol. 2017 May;69(5):964­975. doi: 10.1002/art.40003.

Golovach IYu, Yehudina YeD. The Role of the Microbiome in spondyloarthritis. Fecal microbiota transplantation in spondyloarthritis: ready for a clinical trial? Klinichna immunolohiia. Alerholohiia. In-fektolohiia. 2019;1(114):52­61. (in Ukrainian).

Kondratiuk VE, Tarasenko OM. A modern view of the pathogenetic aspects of gout (review). Ukraiїns'kij revmatologìčnij žurnal. 2018;4(74):32­37. (in Ukrainian).

Jenks K, Stebbings S, Burton J, Schultz M, Herbison P, Highton J. Probiotic therapy for the treatment of spondyloarthritis: a randomized controlled trial. J Rheumatol. 2010 Oct;37(10):2118­25. doi: 10.3899/jrheum.100193.

Pineda Mde L, Thompson SF, Summers K, de Leon F, Pope J, Reid G. A randomized, double­blind, placebo­controlled pilot study of probiotics in active rheumatoid arthritis. Med Sci Monit. 2011 Jun;17(6):CR347­54. doi: 10.12659/msm.881808.

Alipour B, Homayouni­Rad A, Vagnef­Mehrabany E, et al. Effects of Lactobacillus casei supplementa-tion on disease activity and inflammatory cytokines in rheumatoid arthritis patients: a randomized dou-ble­blind clinical trial. Int J Rheum Dis. 2014 Jun;17(5):519­27. doi: 10.1111/1756­185X.12333.

Vagnef­Mehrabany E, Alipour B, Homayouni­Rad A, Sharif SK, Asghani­Jafarabadi M, Zavvari S. Pro-biotic supplementation improves inflammatory status in patients with rheumatoid arthritis. Nutrition. 2014 Apr;30(4):430­5. doi: 10.1016/j.nut.2013.09.007.

Zamani B, Golkar HR, Farshbaf S, et al. Clinical and metabolic response to probiotic supplementation in patients with rheumatoid arthritis: a randomized, double­blind, placebo­controlled trial. Int J Rheum Dis. 2016 Sep;19(9):869­79. doi: 10.1111/1756­185X.12888.

Mohammed AT, Knattab M, Ahmed AM, et al. The therapeutic effect of probiotics on rheumatoid ar-thritis: a systematic review and meta­analysis of randomized control trials. Clin Rheumatol. 2017 Dec;36(12):2697­2707. doi: 10.1007/s10067­017­3814­3.

Aqaeinezhad Rudbane SM, Rahmdel S, Abdollahzadeh SM, Zare M, Bazrafshan A, Mazloomi SM. The efficacy of probiotic supplementation in rheumatoid arthritis: a meta­analysis of randomized, controlled trials. Inflammopharmacology. 2018 Feb;26(1):67­76. doi: 10.1007/s10787­017­0436­y.

Mendoza FA, Purohit S, Kenyon I, Jimenez SA. Severe eosinophilic syndrome associated with the use of probiotic supplements: a new entity? Case Rep Rheumatol. 2012;2012:934324. doi: 10.1155/2012/934324.

Ouwehand AC, Rijkers GT. Severe eosinophilic syndrome: highly unlikely associated with the use of probiotic supplements! Case Rep Rheumatol. 2013;2013:769127. doi: 10.1155/2013/769127.






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