DOI: https://doi.org/10.22141/2224-1507.9.3.2019.178642

Vitamin D status in patients with nontraumatic transient loss of consciousness (literature review)

T.A. Kovalchuk, O.R. Boyarchuk

Abstract


The article presents an analysis of the recent scientific findings on vitamin D status in patients with different etiopathogene­tic varieties of nontraumatic transient loss of consciousness. The results of recent researches suggest that vitamin D may play an indirect and, in some cases, direct role in the pathogenesis of nontraumatic transient loss of consciousness. Data on the cause-effect relationship between a low vitamin D status and syncope are mixed, controversial and ambiguous, which is largely due to the use of different doses of vitamin D, its initial concentration, duration of therapy, genetic diffe­rences in the vitamin D receptors, different age groups, physical parameters of the surveyed, medications, peculiarities of nutrition with special supplements, differences in physical activity, peculiarities of the climate and season, and others. Until now there is no convincing evidence of the benefits of using vitamin D in the treatment and prevention of syncope. Most studies are observational and relate mainly to adult populations. Therefore, randomized controlled studies focused on children may be a promising field of research.


Keywords


nontraumatic transient loss of consciousness; reflex syncope; orthostatic hypotension; cardiogenic syncope; epilepsy; psychogenic syncope; vitamin D; review

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References


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