«Vegetative Passport» and Rehabilitation Diagnosis in the Arthrologic Practice

V.M. Sokrut, O.P. Sokrut, O.V. Syniachenko


The problem of establishing so-called rehabilitation diagnosis (RD) based on the International Classification of Functioning, Disability and Health is still little-known side of the doctor’s and psychologist’s practice. At the moment, there are no unified approaches to establishing RD by the different experts, completely missing general principles of RD for arthrologic group of patients, satisfying medical rehabilitation specialists or rheumatologists, however, the joint disease may be a certain model for solving the problem under discussion. This has become the purpose and the objective of this study.
Materials and methods. Proposed scientific concept was based on the analysis of survey results and on the effectiveness of subsequent rehabilitation of 643 patients suffering from joint diseases with various pathogenesis: 249 people with rheumatoid arthritis, 89 — with chronic gouty arthritis, 305 — with osteoarthritis.
Results. The necessity of RD, which is derived from clinical and functional diagnosis, is generally accepted throughout the world, but so far is little known among domestic rehabilitologists and is not used in the practice of rheumatologists, and RD is exactly a certain «key» of successful measures in rehabilitation treatment of patients suffering from joint diseases. The basis of RD classification was the principle of distribution of patients depending on the type of autonomic nervous system (vagotonics, sympathotonics and eutonics), on which the effectiveness of rehabilitation measures closely depends, with determination of the so-called «vegetative passport». If among healthy people of the same gender and age, the distribution of vagotonics, sympathotonics and eutonics was 1 : 3 : 5, then among the patients with rheumatoid arthritis, the persons with the dominance of sympathetic activity (sympathicotonics) significantly prevailed, and among other groups of patients with chronic joint disorders — of parasympathetic one (parasympathotonics). The major mediator for vagotonics is acetylcholine, and for sympathotonics — noradrenaline.
Conclusion. The proposed RD for rheumatoid, gouty arthritis and osteoarthritis based on «vegetative passport», degree of functional disorders of the musculoskeletal system, parameters of altered homeostasis and somatogenical forms will be ­adopted by rehabilitation specialists and rheumatologists in their practice, and on the proposed principles, further development and implementation of RD, mediated through types of autonomic nervous system, will take the rightful place in other specialists’ practice.


Joints; Autonomic nervous system; Rehabilitation


Aydin T. Evaluation of the effectiveness of home based or hospital based calisthenic exercises in patients with ankylosing spondylitis / T. Aydin, O. Taspinar, M.A. Sariyildiz et al. // J. Back Musculoskelet. Rehabil. — 2016. — Vol. 19, № 2. — P. 177-184.

Beckmann J. Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis / J. Beckmann, J. Schubert, H.G. Morhenn et al. // Cell. Tissue. Res. — 2015. — Vol. 359, № 2. — P. 465-477.

Beckmann J. Effect of M3 muscarinic acetylcholine receptor deficiency on collagen antibody-induced arthritis / J. Beckmann, N. Dittmann, I. Schütz et al. // Arthritis Res. Ther. — 2016. — Vol. 18, № 1. — P. 17-27.

Bogdanova Y. Computerized cognitive rehabilitation of attention and executive function in acquired brain injury: A systematic review / Y. Bogdanova, M.K. Yee, V.T. Ho, K.D. Cicerone // J. Head Trauma Rehabil. — 2015. — Vol. 24, № 12. — P. 153-159.

Dalbeth N. Survey definitions of gout for epidemiological studies: Comparison with crystal identification as the gold standard / N. Dalbeth, H. R. Schumacher, J. Fransen J. et al. // Arthritis Care. Res. — 2016. — Vol. 25, № 3. — P. 173-178.

Gupta A.D. Rethinking diagnoses in rehabilitation: An educational case series / A.D. Gupta, D. Wilson // J. Rehabil. Med. — 2016. — Vol. 22, № 3. — P. 182-188.

Jänig W. Acute inflammation in the joint: its control by the sympathetic nervous system and by neuroendocrine systems / W. Jänig, P.G. Green // Auton. Neurosci. — 2014. — Vol. 182, № 5. — P. 42-54.

Kerschan-Schindl K. Prevention and rehabilitation of osteoporosis / K. Kerschan-Schindl // Wien Med. Wochenschr. — 2016. — Bd. 166, № 1–2. — S. 22-27.

Koopman F.A. Vagus nerve stimulation: a new bioelectronics approach to treat rheumatoid arthritis? / F.A. Koopman, P.R. Schuurman, M.J. Vervoordeldonk, P.P. Tak // Best Pract. Res. Clin. Rheumatol. — 2014. — Vol. 28, № 4. — P. 625-635.

Kröz M. Reduction of endogenous regulation in internal medicine patients / M. Kröz, H. Broder von Laue, R. Zerm et al. // Forsch. Komplementarmed. Klass. Naturheilkd. — 2015. — Bd. 12, № 6. — S. 333-341.

Levine Y.A. Neurostimulation of the cholinergic anti-inflammatory pathway ameliorates disease in rat collagen-induced arthritis / Y.A. Levine, F.A. Koopman, M. Faltys et al. // PLoS One. — 2014. — Vol. 9, № 8. — E. 104530.

Liu Y. Activation of α7 nicotinic acetylcholine receptors prevents monosodium iodoacetate-induced osteoarthritis in rats / Y. Liu, D. Wu, F. Song et al. // Cell. Physiol. Biochem. — 2015. — Vol. 35, № 2. — P. 627-638.

Mandl P. Nicotinic acetylcholine receptors modulate osteoclastogenesis / P. Mandl, S. Hayer, T. Karonitsch et al. // Arthritis Res. Ther. — 2016. — Vol. 18, № 1. — P. 63-73.

Muschter D. Sympathetic neurotransmitters modulate osteoclastogenesis and osteoclast activity in the context of collagen-induced arthritis / D. Muschter, N. Schäfer, H. Stangl et al. // PLoS One. — 2015. — Vol. 10, № 10. — P. 0139726.

Negrini S. Methodology of «Physical and rehabilitation medicine practice, evidence based position papers: the European position» produced by the UEMS-PRM section / S. Negrini, C. Kiekens, M. Zampolini et al. // Eur. J. Phys. Rehabil. Med. — 2016. — Vol. 52, № 1. — P. 134-141.

Novikova D.S. Prospects for the assessment of cardiac rhythm variability in patients with rheumatoid arthritis and systemic lupus erythematosus / D.S. Novikova, T.V. Popkova, T.A. Lisitsyna, E.L. Nasonov // Vestn. Ross. Akad. Med. Nauk. — 2010. — № 9. — P. 23-34.

Park Y. Effects of rehabilitation for pain relief in patients with rheumatoid arthritis: a systematic review / Y. Park, M. Chang // J. Phys. Ther. Sci. — 2016. — Vol. 28, № 1. — P. 304-308.

Richardson B.R. Physiotherapy assessment and diagnosis of musculoskeletal disorders of the knee via telerehabilitation / B.R. Richardson, P. Truter, R. Blumke, T.G. Russell // J. Telemed. Telecare. — 2016. — Vol. 15, № 3. — P. 146-152.

Stewart H. Remote patient monitoring / H. Stewart // JEMS. — 2015. — Vol. 11, № 11, suppl. — P. 5-6.

Thyberg I. Hand pains in women and men in early rheumatoid arthritis, a one year follow-up after diagnosis. The Swedish TIRA project / I. Thyberg, O. Dahlström, M. Björk et al. // Disabil. Rehabil. — 2016. — Vol. 11, № 1. — P. 1-10.

Van Maanen M.A. Two novel α7 nicotinic acetylcholine receptor ligands: in vitro properties and their efficacy in collagen-induced arthritis in mice / M.A. Van Maanen, R.L. Papke, F.A. Koopman et al. // PLoS One. — 2015. — Vol. 10, № 1. — E. 0116227.

Yi L. α7 nicotinic acetylcholine receptor is a novel mediator of sinomenine anti-inflammation effect in macrophages stimulated by lipopolysaccharide / L. Yi, J.F. Luo, B.B. Xie et al. // Shock. — 2015. — Vol. 44, № 2. — P. 188-195.

DOI: https://doi.org/10.22141/2224-1507.1.21.2016.74091


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