Mineral Density and Quantity of Bone, Parameters of Body Composition in Postmenopausal Women

O. Ivanyk


In diagnostic of osteoporosis the golden standard is bone mineral density, though X-ray densitomenry parameters not always determine risk for osteoporotic fractures. That is why new methods are being looked for to find the parameters not only mineral density, but rather quantity of bone. One of theses methods is trabecular bone score. As general weight of body includes fat and lean mass some researchers tried to determine their role in development of structural and functional impairments in bone, however there is no clear answer to this question: while some scientists considered fat mass as a basic factor of protection from fractures, other ones decided that lean mass is more connected with mineral density of bone tissue. The aim of study was to investigate parameters of quantity and density of bone of spine, neck of femur and body composition depending on the postmenopausal period; to study connection between fat mass and mineral density and quantity of bone. Materials and methods. The observed females were divided into the groups: premenopausal women and women with postmenopause of various duration (early, middle, late). There were conducted a general clinical observation of a patient and investigation of mentioned above parameters using X-ray densitomentry General Electric. Results. Quantity of bone (TBS) and bone mineral density significantly decrease depending on postmenopausal period. Fat and lean masses do not significantly change. In the middle and late postmenopausal periods bone mineral density of the spine and hip neck increase while fat mass increases.


osteoporosis; bone mineral density; TBS; fat mass; lean mass; postmenopausal osteoporosis.


Поворознюк В.В., Дзерович Н.И. Качество трабекулярной костной ткани у женщин различного возраста // Боль. Суставы. Позвоночник. — 2011. — 4. — С. 29-31.

Поворознюк В.В., Дзерович Н.И. Качество трабекулярной костной ткани у женщин в зависимости от длительности постменопаузального периода // Боль. Суставы. Позвоночник. — 2012. — 2. — С. 11-15.

Поворознюк В.В. Постменопаузальний остеопороз: механізми розвитку, фактори ризику, клініка, діагностика, профілактика та лікування // Педіатрія, акушерство та гінекологія. — 1998. — 2. — С. 98-111.

Поворознюк В.В., Боріс О.М. Зв’язок між структурно-функціональним станом кісткової тканини та антропометричними показниками у жінок в пре- та постменопаузальному періоді // Захворювання кістково-м’язової системи в людей різного віку (вибрані лекції, огляди, статті). — 2004. — Т. 1. — С. 459-478.

Boutroy S., Hans D., Sornay-Rendu E. et al. Trabecular bone score improves fracture risk prediction in non-osteoporotic women: the OFELY study // Osteoporos Int. — 2013. — 24 (1). — P. 77-85.

Hans D., Goertzen A.L., Krieg M.A. et al. Bone microarchitecture assessed by TBS predicts osteoporotic fractures independent of bone density: the Manitoba study // J. Bone Miner. Res. — 2011. — 26. — P. 2762-2769.

Cormier C., Lamy O., Poriau S. TBS in routine clinical practice: proposals of use. Atlas of TBS use // Edition. — 2012. — 16 p.

Hans D., Winzenrieth R. Estimation of Bone microarchitecture Pattern from AP spine DXA scansusing the Trabecular Bone Score (TBS): An added value in clinical routine for the patient. A short revive // Osteologicky bulletin. — 2011. — 16 (3). — P. 70-78.

Winzenrieth R., Dufour R., Pothuaud L. et al. A retrospective Case-control study assessing the role of trabecular bone score in postmenopausal caucasian women with osteopenia: analysing the odds of vertebral fracture // Calcif. Tissue Int. — 2010. — 86. — P. 104-109.

Leslie W.D., Kanis J. Lumbar spine TBS is a FRAX independent risk factor for fracture. The Manitoba BMD Cohort // Program and abstract book (ISCD Annual meeting 2013, Tampa, Florida). — 2013. — P. 12-15.

Bousson V., Bergot C., Sutter B. еt al. Trabecular bone score (TBS): available knowledge, clinical relevance, and future prospects // Osteoporos Int. — 2012. — 23 (5). — P. 1489-1501.

Roux C. Osteoporosis in inflammatory joint diseases // Osteoporos Int. — 2011. — 22. — P. 421-433.

Sinigaglia L., Nervetti A., Mela Q. et al. A multicenter crosssectional study on bone mineral density in rheumatoid arthritis. Italian Study Group on Bone Massin Rheumatoid Arthritis // J. Rheumatol. — 2000. — 27. — P. 2582-2589.

Gunther C. et al. Beneficial Effect of PTH on Spine BMD and Microarchitecture (TBS) Parameters in Postmenopausal Women with Osteoporosis. A 2-Year Study // Osteoporosis Int. — 2012. — 23 (2). — S. 85-386.

Kanis J.A. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report // Osteoporosis Int. — 1994. — 4. — P. 368.

Povoroznyuk V.V., Dzerovich N.I., Karasevskaya T.A. Bone mineral density in Ukrainian women of different age // Ann. N. Y. Acad. Sci. — 2007. — 1119. — P. 243-252.

Vasic J., Petranova T., Povoroznyuk V. et al. Evaluating spine micro-architectural texture (via TBS) discriminates major osteoporotic fractures from controls both as well as and independent of site matched BMD: the Eastern European TBS study // J. Bone Miner Metab. — 2014. — 32 (5). — P. 556-562.

Kim W., Chung S.G., Kim K. et al. The relationship between body fat and bone mineral density in Korean men and women // J. Bone Miner Metab. — 2014. — 32 (6). — P. 709-717.

Machado L.G., Domiciano D.S., Figueiredo C.P. et al. Visceral fat measured by DXA is associated with increased risk of non-spine fractures in nonobese elderly women: a population-based prospective cohort analysis from the São Paulo Ageing & amp; Health (SPAH) Study // Osteoporos Int. — 2016. — P. 17-20.

Goh V.H., Hart W.G. Aging and bone health in Singaporean Chinese pre-menopausal and postmenopausal women // Maturitas. — 2016. — 89. — P. 16-21.

DOI: https://doi.org/10.22141/2224-1507.2.22.2016.75765


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