Early Rheumatoid Arthritis without Radiographic Erosions: MRI Diagnostic Capabilities

D.V. Vershynina

Abstract


The results of clinical and radiological examination of 65 patients with early rheumatoid arthritis with joint syndrome duration up to 12 months were presented in the article. The incidence of radiographic erosions in conventional X-ray and magnetic resonance imaging (MRI) depending on the clinical and laboratory features was analyzed. A standard protocol of examination and a sequence of images evaluation were developed. MRI is more informative method for topical diagnosis of early arthritis compared to conventional radiography. MRI made it possible to diagnose erosive changes in the joints of 36 patients out of 65 in early rheumatoid arthritis that is significantly greater than with conventional X-ray examination (in 2 patients out of 65). Using MRI, erosive changes in the hand joints were diagnosed 12 months prior to their detection on radiograms, the most significant differences in the definition of destructive changes occur in the carpal bones and heads of metacarpal bones. The rate of wrist erosions detection on MRI correlated with seropositivity for antibodies to cyclic citrullinated peptides and did not depend on the process activity by DAS28.


Keywords


early rheumatoid arthritis; conventional X-ray; magnetic resonance imaging; hand joints; erosion; diagnosis

References


Вершинина Д.В., Головач И.Ю. Клинические, рентгенологические, МР-томографические и денситометрические сопоставления при раннем ревматоидном артрите // Журнал Гродненского гос. мед. унив. — 2014. — № 48. — С. 32-36.

Гармиш Е.А. Сравнительная оценка диагностических возможностей рентгенографии и магнитно-резонансной томографии на ранних стадиях ревматоидного артрита и в динамике лечения лефлуномидом, натрием ауротиомалатом и метотрексатом // Укр. ревматол. журнал. — 2005. — № 1. — С. 74-78.

Труфанов Г.Е. Лучевая диагностика повреждений и заболеваний лучезапястного сустава и запястья / Г.Е. Труфанов, И.Г. Пчелин, Е.А. Кадубовская. — СПб.: ЭЛБИ-СПб, 2013. — 496 с.

Aletaha D., Neogi T., Silman A.J. et al. Rheumatoid Arthritis Classification Criteria. An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative // Arthritis Rheum. — 2010. — Vol. 62, № 9. — P. 2569-2581.

Backhaus M., Sandrock D., Schmidt W.A. Imaging in rheumatology // Dtsch. Med.Wochenschr. — 2002. — Vol. 127(37). — Р. 1897-1903.

Conaghan P., Bird P., Ejbjerg B. et al. The EULAR ­OMERACT rheumatoid arthritis MRI reference image atlas: the metacarpophalangeal joints // Ann. Rheum. Dis. — 2005. — Vol. 64 (Suppl. 1). — P. 11-21.

Ejbjerg B.J., Vestergaard A., Jacobsen S. et al. The smallest detectable difference and sensitivity to change of magnetic resonance imaging and radiographic scoring of structural joint damage in rheumatoid arthritis finger, wrist, and toe joints: a comparison of the OMERACT rheumatoid arthritis magnetic resonance imaging score applied to different joint combinations and the Sharp/van der Heijde radiographic score // Arthritis Rheum. — 2005. — Vol. 52(8). — P. 2300-2306.

Kosta P.E., Voulgari P.V., Zikou A.K. et al. The role of very early diagnosis and treatment of rheumatoid arthritis in the reversibility of bone edema, synovitis and bone erosions evaluated by magnetic resonance imaging of the dominant hand // Ann. Rheum. Dis. — 2010. — Vol. 69 (Suppl. 3). — Р. 306.

McQueen F.M., Stewart N., Crabbe J. et al. Magnetic resonance imaging of the wrist in early rheumatoid arthritis reveals progression of erosions despite clinical improvement // Ann. Rheum. Dis. — 1999. — Vol. 58(3). — P. 156-163.

Nishimura K., Sugiyama D., Kogata Y. et al. Meta-ana­lysis: diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthritis // Ann. Inter. Med. — 2007. — Vol. 146(11). — P. 797-808.

Østergaard M., Edmonds J., McQueen F. et al. An introduction to the EULAR-OMERACT rheumatoid arthritis MRI reference image atlas // Ann. Rheum. Dis. — 2005. — Vol. 64, Suppl. 1. — P. 3-7.

Sharp J.T. Radiologic assessment as an outcome measure in rheumatoid arthritis // Arthritis Rheum. — 1989. — Vol. 32. — P. 221-229.

Sokka T. Radiographic Scoring in Rheumatoid Arthritis A Short Introduction to the Methods // Bul. NYU Hosp. Joint Dis. — 2008. — Vol. 66(2). — P. 166-168.

Solanki K., Spellerberg M., Chapman P. et al. Anti-cyclic citrallinated antibodies: complementary to IgM rheumatoid factor in the early diagnosis of rheumatoid arthritis // N.Z. Med. J. — 2004. — Vol. 8(117). — P. 1097.

Steinbrocker O., Traeger C.H., Batterman R.C. Therapeutic criteria in rheumatoid arthritis // JAMA. — 1949. — Vol. 140, № 8. — P. 659-662.

Van der Heijde D., Boers M., Lassere M. Methodological issues in radiographic scoring methods in rheumatoid arthritis // J. Rheumatol. — 1999. — Vol. 26. — P. 726-730.




DOI: https://doi.org/10.22141/2224-1507.2.18.2015.79102

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