Mineral density and bone metabolism in patients with spinal cord trauma

V.V. Povoroznyuk, M.A. Bystritskaya

Abstract


 In a study cited in the article, it is proved that in patients with traumatic spinal cord disease mineral bone density (MBD) were significantly lower than in healthy persons, while MBD significantly shorter in patients with traumatic disease. This has led to the conclusion that severe damage to the spinal cord with a profound motor deficit leads to a rapid loss of bone mass in the first years after the injury, with the development of secondary osteoporosis, which progresses with the duration of traumatic disease. Monitoring MBD in this category of patients will allow to distinguish patients with high risk of fractures and timely correction of bone and prevent fractures.


Keywords


mineral density of bone tissue; injury; risk

References


Белова А.Н. Нейрореабилитация: Руководство для врачей. — М.: Антидот, 2000. — С. 172-180, 347-404.

Брюховецкий А.С. Травма спинного мозга: клеточные технологии в лечении и реабилитации. — М.: Практическая медицина, 2010. — 341 с.

Morse L., Battaglino R. et al. Osteoporotic fractures and hospitalization risk in chronic spinal cord injury // Osteoporos Int. — 2009. — № 20(3). — Р. 385-392.

Mechanick J., Liu K. et al. Effect of a Convenient Single 90-mg Pamidronate Dose on Biochemical Markers of Bone Metabolism in Patients With Acute Spinal Cord Injury // J. Spinal Cord Med. — 2006. — № 29(4). — Р. 406-412.

Modlesky C., Slade J. et al. Deteriorated geometric structure and strength of the midfemur in men with complete spinal cord injury // Bone. — 2005. — № 36. — Р. 331-339.

Krause J., Carter R. et al. A prospective study of health and risk of mortality after spinal cord injury // Arch. Phys. Med. Rehabil. — 2008. — № 89. — Р. 1482-1491.

Garland D., Adkins R. Bone loss at the knee in spinal cord injury // Top Spinal Cord. Inj. Rehabil. — 2001. — № 6. — Р. 37-46.

Rittweger J., Gerrits K. et al. Bone adaptation to altered loading after spinal cord injury: a study of bone and muscle strength // J. Musculoskelet Neuronal Interact. — 2006. — №. 6. — Р. 269-276.

Shields R., Dudley-Javoroski S. et al. Peripheral quantitative computed tomography: measurement sensitivity in persons with and without spinal cord injury // Arch. Phys. Med. Rehabil. — 2006. — № 87. — Р. 1376-1381.

Bryson J. Bisphosphonate Use in Acute and Chronic Spinal Cord Injury: A Systematic Review // Osteoporos Int. — 2010. — № 21(6). — Р. 985-995.




DOI: https://doi.org/10.22141/2224-1507.1.05.2012.82204

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