Evaluation the Potential of the Austrian FRAX Model Use in Predicting the Risk for Osteoporotic Fractures in Ukrainian Women

V.V. Povoroznyuk, N.V. Grigoryeva

Abstract


Currently FRAX is informative and independent tool in assessment of risk for osteoporotic fractures. In order to create normative data for Austrian FRAX model algorithm we have examined 3405 women aged 40–89 years. Analysis of FRAX results revealed that FRAX-all and FRAX-hip performance, respectively, 11.5 and 2.5 points when using the Austrian model in postmenopausal women are the criteria for initiation of therapy for osteoporosis. Indicators of FRAX-all and FRAX-hip respectively 7.0 and 1.5 points when using the Austrian model in postmenopausal women are additional criteria for additional examination of patients with two-photon X-ray densitometry.
We have developed criteria that can be used to make the decision to start antiosteoporotic therapy, especially if you can not carry out X-ray densitometry.


Keywords


osteoporosis; FRAX; diagnosis; risk factors

References


Поворознюк В.В., Григорьева Н.В. Роль FRAX в прогнозировании риска переломов // Боль. Суставы. Позвоночник. — 2011. — № 2. — С. 19-28.

Поворознюк В.В., Григорьева Н.В. Информативность различных моделей FRAX в оценке риска остеопоротических переломов у женщин Украины // Боль. Суставы. Позвоночник. — 2013. — № 2. — С. 19-28.

Clinician’s guide to prevention and treatment of osteoporosis // National Osteoporosis Foundation. — 2013. — 54 p.

Interpretation and Use of FRAX® in Clinical Practice from the International Society for Clinical Densitometry and International Osteoporosis Foundation. — 2010. — 12 р.

Kanis J.A., Johnell O., Oden A. et al. FRAX and the assessment of fracture probability in men and women from the UK // Osteoporos. Int. — 2008. — № 19. — Р. 385-397.

Kanis J.A., on behalf of the World Health Organization Scientific Group: Assessment of Osteoporosis at the Primary Health-Care Level // Technical report. University of Sheffield, UK: WHO Collaborating Centre; 2008.

Kanis J.A., Johansson H., Oden A. et al. The effects of a FRAX revision for the USA // Osteoporos. Int. — 2010. — 21(1). — P. 35-40.

Kanis J.A., Odén A., McCloskey E.V. et al. and on behalf of the IOF Working Group on Epidemiology and Quality of Life A systematic review of hip fracture incidence and probability of fracture worldwide // Osteoporos. Int. — 2012. — 23(9). — P. 2239-2256.

Kanis J.A., McCloskey E.V., Johansson H. et al. and on behalf of the Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the Committee of Scientific Advisors of the International Osteoporosis Foundation (IOF) European guidance for the diagnosis and management of osteoporosis in postmenopausal women // Osteoporos. Int. — 2013. — 24(1). — P. 23-57.

Van den Bergh J.P.W, van Geel T.A.C.M., Lems W.F., Geusens P.P. Assessment of Individual Fracture Risk: FRAX and Beyond // Curr. Osteoporos. Rep. — 2010. — 8(3). — P. 131-137.




DOI: https://doi.org/10.22141/2224-1507.3.11.2013.82322

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