Sarcopenia, Osteoporosis and Its Complications

V.V. Povoroznyuk, N.I. Dzerovych


Today, the significant attention of scientists is paid to the study of associative changes in muscle and bone tissue with age. The reduction of muscle mass and its function is associated with reduced bone mineral density, increased risk of falls, deterioration in the quality of life, functionality and increased patient mortality. However, there is a small number of studies that have examined the relationship between sarcopenia and osteoporotic fractures. The aim of research: to study the particularities of body composition, structural and functional state of bone in women aged 65 and older depending on the presence of vertebral deformations. We have examined 171 women aged 65–89 years. Depending on the presence of vertebral deformations, the patients were divided into two groups: A — 105 women without vertebral deformations, B — 66 women with vertebral deformations. Lean and fat masses, bone mineral density and trabecular bone score, lateral vertebral assessment were performed by dual X-ray absorptiometry (Prodigy, GEHC Lunar, Madison, WI, USA). We determined that patients with vertebral deformations as compared to the women without deformations had significantly lower indices of bone mineral density, trabecular bone score, lean and fat masses (p < 0.05). The incidence of presarcopenia (reduced lean mass) in women with vertebral deformations was 14.6 %, in women without vertebral deformations — 2.2 %.


muscle tissue; lean mass; bone mineral density; osteoporosis; vertebral deformations; women


Поворознюк В.В. Захворювання кістково-м’язової системи в людей різного віку (вибрані лекції, огляди, статті): У 3 т. — ​К., 2009. — ​С. 664.

Поворознюк В.В., Дзерович Н.І. Мінеральна щільність кісткової тканини, особливості тілобудови тіла жінок літнього віку з остеопоротичними деформаціями тіл хребців // Травма. — 2014. — ​Т. 15, № 6. — ​С. 24-27.

Поворознюк В.В., Бінклі Н., Дзерович Н.І., Поворознюк Р.В. // Саркопенія. — ​К.: ПАТ «Віпол», 2016. — 180 с.

Adamczyk P., Morawiec-Knysak A., Płudowski P. et al. Bone metabolism and the muscle-bone relationship in children, adolescents and young adults with phenylketonuria // J. Bone Miner. Metab. — 2011. — ​Vol. 29. — ​P. 236-244.

Burton L.A., Sumukadas D. Optimal management of sarcopenia // Clinical interventions in aging. — 2010. — 5. — ​P. 217-228.

Cruz-Jentoft A.J., Baeyens J.P., Bauer J.M et al. Sarcopenia: European consensus on definition and diagnosis // Age and ageing. — 2010. — 39. — ​P. 412-423.

Cui L.H., Shin M.H., Kweon S.S. et al. Relative contribution of body composition to bone mineral density at different sites in men and women of South Korea // J. Bone Miner. Metab. — 2007. — ​Vol. 25, № 3. — ​P. 165-171.

Di Monaco M., Vallero F., Di Monaco R. et al. Prevalence of sarcopenia and its association with osteoporosis in 313 older women following a hip fracture // Arch Gerontol. Geriatr. — 2011. — 52(1). — ​P. 71-4.

Faje A., Klibanski A. Body composition and skeletal health: too heavy? Too thin? // Curr. Osteoporos. Rep. — 2012. — ​Vol. 10, № 3. — ​P. 208-216.

Gentil P., Lima R.M., Jaco de Oliveira R. et al. Association between femoral neck bone mineral density and lower limb fat-free mass in postmenopausal women // J. Clin. Densitom. — 2007. — ​Vol. 10, № 2. — ​P. 174-178.

Gnudi S., Sitta E., Fiumi N. Relationship between body composition and bone mineral density in women with and without osteoporosis: relative contribution of lean and fat mass // J. Bone Miner. Metab. — 2007. — ​Vol. 25, № 5. — ​P. 326-332.

Hida T., Ishiguro N., Shimokata H. et al. High prevalence of sarcopenia and reduced leg muscle mass in Japanese patients immediately after a hip fracture // Geriatr. Gerontol. Int. — 2013. — 13(2). — ​P. 413-20.

Kaji H. Interaction between muscle and bone // J. Bone Metab. — 2014. — 21. — ​Р. 29-40.

Karasik D., Kiel P. Evidence for pleiotropic factors in genetics of the musculoskeletal system // Bone. — 2010. — ​Vol. 46(5). — ​P. 1226-1237.

Kirchengast S., Huber J. Sex-specific associations between soft tissue body composition and bone mineral density among older adults // Ann. Hum. Biol. — 2012. — ​Vol. 39. — ​

P. 206-213.

Lang T., Streeper T., Cawthon P. et al. Sarcopenia: etio­logy, clinical consequences, intervention and assessment // Osteoporos Int. — 2010. — 21. — ​P. 543-559.

Lee I., Ha Ch., Kang H. Association of sarcopenia and phy­sical activity with femur bone mineral density in elderly women // J. Exerc. Nutrition Biochem. — 2016. — 20(1). — ​P. 23-28.

Lima R.M., Bezerra L.M. et al. Fat-free mass, strength, and sarcopenia are related to bone mineral density in older women // J. Clin. Densitom. — 2009. — ​Vol. 12. — ​P. 35-41.

Orsatti F., Nahas E., Nahas-Neto J. et al. Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women // BMC Musculoskeletal Di­sorders. — 2011. — 12. — ​P. 225.

Sjöblom S., Suuronen J., Rikkonen T. et al. Relationship between postmenopausal osteoporosis and the components of clinical sarcopenia // Maturitas. — 2013. — ​Vol. 75. — ​P. 175-180.

Sunyoung K., Won Won C., Sung Kim B. et al. The association between the low muscle mass and osteoporosis in elderly korean people // Korean Med. Sci. — 2014. — ​Vol. 29. — ​P. 995-1000.

Verschueren S., Gielen E., O’Neill T.W. et al. Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men // Osteoporos Int. — 2013. — 24 (1). — ​P. 87-98.

Walsh M.C., Hunter G.R. Sarcopenia in women with osteopenia, osteoporosis and normal bone mineral density // Osteoporosis Int. — 2007. — ​Vol. 18. — ​P. 42-47.

Walsh M.C., Hunter G.R., Livingstone M.B. Sarcopenia in premenopausal and postmenopausal women with osteopenia, osteoporosis and normal bone mineral density // Osteoporosis Int. — 2006. — 17. — ​P. 61-67.



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