@article{Povoroznyuk_Dzerovych_Povoroznyuk_2018, title={Bone mineral density, spinal micro-architecture (TBS data) and body composition in the older Ukrainian women with vertebral fragility fractures}, volume={8}, url={https://pjs.zaslavsky.com.ua/index.php/journal/article/view/240}, DOI={10.22141/2224-1507.8.4.2018.154131}, abstractNote={Osteoporosis and sarcopenia are the most frequent musculoskeletal disorders affecting older people. Fracture incidence as well as the number of fractures increase due to the population’s ageing. Recent studies show that a low skeletal muscle mass is associated with the poor structural bone parameters and impaired balance in the elderly people. The aim of this study is to evaluate the bone mineral density (BMD), trabecular bone score (TBS) and body composition in women taking into account the presence of vertebral fragility fractures (VFF). We’ve examined 171 women aged 65–89 years (mean age — 73.12 ± 0.39 years). The patients were divided into the groups depen­ding on VFF presence: A — no VFF (n = 105), B — detected VFF (n = 66). Total body, lumbar spine, femoral neck, forearm BMD, lateral vertebral assessment, lean and fat mass measurement were performed on densitometer (Prodigy, GE). Appendicular lean mass (ALM) was measured at all the four limbs with dual energy X-ray absorptiometry (DXA). We’ve also calculated the appendicular lean mass index (ALMI) according to the equation: ALMI = ALM, kg / height, m2 (kg/m2). TBS (L1-L4) was assessed by TBS iNsight® software package installed on our DXA machine (Med-Imaps, Pessac, France). Statistiсa© 6.0 StatSoft, Inc. was used for data processing purposes. Significance was set at p < 0.05. We have found the following parameters to be significantly lower in women with VFF compared to women having no VFF: BMD of total body, spine, femoral neck, 33% forearm, TBS, whole-body fat mass, whole-body lean mass, ASM and ASMI (p < 0.05). The frequency of presarcopenia was significantly higher in women with osteoporosis (21.2 %) and osteopenia (21.5 %) compared to women who had normal BMD (6.7 %). The frequency of presarcopenia was 2 % in women with no VFF and 14 % — in women with VFF. Thus, women with VFF have significantly lower BMD, TBS, lean and fat masses data as compared to women with no VFF.}, number={4}, journal={PAIN, JOINTS, SPINE}, author={Povoroznyuk, V. and Dzerovych, N. and Povoroznyuk, R.}, year={2018}, month={Dec.}, pages={144–149} }